Increasing the quantity and quality of food in Africa will be critical to improving the continent’s human development. And a key element in giving Africa a more secure food supply will be boosting science and knowledge on the continent and making sure it is focused on Africa’s needs and situation.
One pioneering scientist is looking to the humble chicken to tackle two big problems in Africa: food security and household incomes. By pumping up the weight and productivity of African chickens, she hopes to eradicate hunger and boost household incomes.
Her pioneering work is about trailblazing “a big chicken agenda in Africa,” she explained to TrustLaw, a global hub for free legal assistance and information on good governance and women’s rights. She grew up in an area – Mount Elgon in western Kenya – where raising chickens was the primary source of both income and food. Her family raised chickens and the income from this helped to pay for her schooling.
Raising chickens is common in rural Kenya, and many of the people doing it are women.
She works at the International Livestock Research Institute (ilri.org) based in Nairobi, Kenya. The ILRI “works at the crossroads of livestock and poverty, bringing high-quality science and capacity-building to bear on poverty reduction and sustainable development” and conducts research in Africa, South and Southeast Asia and China.
“I’m really passionate about giving back to the community an improved chicken that will really help their lives,” she explains.
Another project she is working on is the development of a drought-tolerant chicken. This chicken could prove very helpful in parts of Africa suffering from drought and hunger, like in the Horn of Africa.
Women are considered to be the majority producers of food in Africa yet just one in four people working in agricultural research in Africa is a woman, according to TrustLaw.
Ommeh has a PhD in chicken genetics and is a staunch believer in seeking out solutions to Africa’s problems within Africa: “In my view = it’s about time Africa looked for solutions in Africa for Africa,” she told a group of British Members of Parliament.
She will continue her research by looking at native African chickens. She is worried indigenous African chickens are being wiped out by cross-breeding and the introduction into the continent of exotic breeds, which are making African chickens more susceptible to viruses.
Her goal is to produce a disease-resistant breed of chicken weighing four kilograms and laying 250 eggs a year. This would be a big increase on current average weights, and a trebling of the yield.
“Definitely the incomes of these households will increase and that will (create) a rippling effect that will trickle up … And we hope that in 10 to 15 years the poverty issue in Africa will not be so serious,” Ommeh said.
“Chicken is a small livestock but I believe it has the capacity to have a big impact.”
For female scientists working in agriculture, African Women in Agricultural Research and Development (AWARD) (http://awardfellowships.org/) is seeking researchers looking to boost their technical and leadership skills. It is hoped that supporting more women researchers will have the effect of turning research priorities towards the needs of smallholder farmers, who make up the majority of farmers in Africa.
In 2001 I was hired to project manage and deliver a Child Health Web Portal for the prestigious Great Ormond Street Children’s Hospital NHS Trust (GOSH)/Institute of Child Health (ICH) based in London, UK.
The project was intended to lead on innovation at the institutions and in the wider National Health Service (NHS) and was delivered in three phases. Screen grabs can be viewed below:
From the start, the project begged the question: Could we take a complex (and complicated) mandate and successfully achieve it in just two years? All under great public and media scrutiny (London being a world centre for media)? And how do you innovate for the 21st century in a major health care institution and build on its already high reputation?
Britain’s best-loved children’s hospital and charity, Great Ormond Street Hospital for Children NHS Trust (GOSH), contracted me to lead a two-year project to modernise the hospital’s web presence and take its brand into the 21st century. GOSH is both Britain’s first children’s hospital and a pioneering child health institution (along with its partner the Institute for Child Health). The hospital’s outstanding reputation meant the project was carried out under intense public, media and professional scrutiny, and required a keen awareness of new media developments and the needs of the hospital’s patients, their families and the public. It drew on an extensive public consultation and the NHS Modernisation Plan and the Information for Health strategy – which had identified strong demand for services and information to be made available online – to develop this innovative online offering. The NHS had also set the goal of having 25 per cent of all its services accessible via the web.
From the start, the project represented a new phase in how the institutions communicated. An announcement in PR Week in April 2001 acknowledged this, declaring the role will deal “with what is increasingly becoming an important part of the press office and the hospital”. Prior to beginning the two-year project in 2001, the existing website was an amateurish affair and not suitable for an internationally renowned centre for paediatric treatment, training and research.
The UK had become out of step with wider web developments at that time and had to do a lot of catching up. But there was a ready audience for better web content already established in the country. By 2001, data showed 3 million children in the UK were using the Internet and 33 million UK citizens could access it through work, school or home.
By 2001, the Internet offered an estimated 100,000 health-related websites (most based in the United States, leaving a gap for high-quality information based on UK research and experience). Trust was key and this was a crucial part of the content strategy that was developed.
As lead staff member for the website, I was in charge of recruiting and managing staff and suppliers, liaising with stakeholders inside and outside the organisations, planning work and seeking opportunities and partnerships.
The project was developed in three, distinct phases. Screen grabs from these phases are available for download and evaluation. They also include web traffic statistics. This unique snapshot of a complex project as it unfolded, should prove useful for other e-health practitioners.
As an innovator, the project became a catalyst for numerous online and offline initiatives across the institutions. The website made enormous strides, winning a number of national and international awards and leapfrogging to become one of the best NHS-linked sites in the UK. Areas radically improved included the design and navigation, patient information for families, press office, and the development and launch of the award-winning children’s website.
Each stage was transparently communicated and accompanied by high-profile publicity campaigns: a necessity because the hospital relies heavily on public trust and funding to function.
The first phase involved getting buy-in on a new design vision, assembling a team, extensive work on migrating the very large legacy website into the new template, and exciting colleagues on the potential of the new child health portal vision. It was launched in September 2001.
Ask Dr Jane Collins, a regular column written by the Chief Executive Dr. Jane Collins for The Times newspaper, was one of the more popular features of the child health portal. The portal was also directly connected to the NHS Direct service with its extensive online health encyclopedia.
As another example, the hospital’s 150th birthday celebration on 14th February 2002, attended by Her Majesty the Queen (and celebrities, including Madonna), was accompanied by an online interactive history prepared by the project and was used to inform the wider public about the child health portal.
Phase two involved the launching of new content developed by some of the world’s top child health experts and scientists, substantial new resources for sick children and their families, an online awareness-raising campaign to drive traffic to the health portal as a trusted and reliable resource, plus a wider media campaign. Based on user experience testing and user feedback, changes were made to the design and content structure to make the portal more user-friendly and to follow best practice in web design at that time.
The overall child health portal also gave birth to a highly successful new resource, the award-winning Children First website in May 2002. This resource was a year in development and was calibrated by age to provide relevant resources to guide children through the hospital experience. It used high-quality animation and partnered with BBCi and BBC Science to create resources that would resonate with children and youth. It included high-profile elements such as the Write4GOSH children’s writing prize, attracting entries from around the world, with winners receiving prizes from Cherie Booth QC, Dannii Minogue and children’s writer Jacqueline Wilson.
Children First attracted an average of 700,000 visitors each month with over 800 children in its first year contributing to the site. It addressed a gap in the online marketplace for health resources written for children rather than for their parents and families. It also gave birth to its own project: The Virtual Children’s Hospital (VCH). Funded by the PPP Foundation in August 2002, it worked with a team of psychologists to meet the social, psychological and information needs of ill children.
In March 2003 the Commission for Health Improvement (CHI) in its review and assessment found, in answer to the question “What, if anything, did CHI find that the rest of the NHS can learn from?” at the hospital, it was the child health portal, because “The trust’s website has different sections for children and families as well as for health professionals. The website also has sections for children of different ages and a broad range of information leaflets is available to download. The website has 3.5 million hits per month.”
In 2003, the UK’s Guardian newspaper called the Children First website one of the “three most admired websites in the UK public and voluntary sectors,” and a UK government assessment called the overall GOSH child health web portal a role model for the NHS. Children First also won the prestigious Cable and Wireless Childnet Award that year as well. And was short-listed for the New Stateman’s New Media Awards.
In 2006, The Times of London called Children First the Top Child Health Website in its Wellbeing on the Web: The Best Portals survey (November 11, 2006).
Phase three saw online traffic growing at a steady clip, the portal gaining accolades, awards and positive reviews; it also helped the hospital to gain the highest rating in a government review (5*), and Children First was awarded significant further funding so it could expand its resources. The award-winning team also re-developed thewww.gosh.org charity website (one of the highest profile charity brands in the UK) and launched it in 2003 as well.
2001: Initial design vision articulated and team assembled. First phase of content creation and ‘soft launch’ of portal in September 2001. Begin experiments with new graphic design, including an online interactive Christmas advent calendar with health tips.
2002: Launch new content during the hospital’s 150th anniversary celebrations; begin development work on Children First content. Partnering with BBCi and BBC Science to improve quality of child and youth resources. Significant new content is launched throughout the year as the portal sees month-on-month growth in web traffic. Awarding of further funding for Children First and the Virtual Children’s Hospital.
2003: Winning of Childnet Award; launch of new GOSH Charity website. Record web traffic to the website.
“As a parent, I recognise how important it is to help your child understand all that they can about their stay in hospital and their care and treatment. Time spent in hospital can often be a very frightening experience. Making sure that your child has helpful, easy to read information will make a significant difference to their time in hospital.
I am sure that this website will prove very useful for children and their families.” Prime Minister Tony Blair, May 2002
“A highly attractive website written by and with children at Britain’s biggest specialist hospital for children. The site is carefully segmented for different age groups and provides a powerful platform on which children can reach out from the confines of their hospital wards, share their experiences and learn about a range of medical issues as well as have access to fun interactive resources.” Childnet Award 2003
“I am glad you mentioned the web site. If you can access it and haven’t recently please have a look. It has vastly improved and both David Latchman and I (it is a joint site with ICH) are very pleased.” Dr Jane Collins, Chief Exec’s Corner, Roundabout newsletter, February 2002
“I never thought that GOSHKids would be so valuable to the hospital or, more importantly, to children and young people attending the hospital or simply interested in health matters. I think that this reflects my age, though!
“Many of us over 30, even if we use the internet ourselves, are surprised how much children and young people use it both as a source of information and for entertainment.
“Even quite young children are using it routinely now and as an increasing number of families have access to it, either at home and/or at school or work, presumably more and more will do so.
“There are over 42,000 hits per day (1,260,000 a month) on our GOSHKids website already. Of course, part of the success of the website is down to its design and content. I would like to take this opportunity to congratulate Gary Loach, David South and the whole team who have worked so hard to make it successful.” Dr Jane Collins, Chief Exec’s Corner, Roundabout newsletter, June 2003
“The GOSH/ICH web site to date has been a notable success. Not only has it met a majority of its objectives as delineated in the PIN report of 2000 and achieved recognition as ‘exemplary’ among NHS resources, but it has also generated a number of spin-off projects, including Children First (as a successor to GOSHKids) and The Virtual Children’s Hospital.
“It has moved from providing a poor representation of the organisations, to above average for corporate web resources, and compares highly favourably with those of other NHS sites and departments. The most notable success lies in the resource it now provided for the public, especially GOSHKids.
“In a context in which less than 25% of all projects realise even 50% of their benefits, the satisfaction of 75% of the original objectives set out in the PIN report must rank as a significant achievement.” Website Project Audit by Passmasters Limited, 17 April 2003
“Great Ormond Street Hospital has launched this health site targeted specifically at childen, with a separate version aimed at young teenagers. The site aims to give young ‘uns information about health, illness and treatment in an easily digestable, non-threatening manner.” Internet Magazine, July 2002
“… it’s a good site and not just for those about to go into the hospital.” New Media Age, 20 June 2002
“The project was instrumental in pulling together a number of key strategies (including the NHS’s Modernisation Plan, and its Information for Health Strategy), and acting as a catalyst for numerous online and offline initiatives. Critical to these strategies is the need to provide information and services online and in an accessible way. The aim has not only been about serving the specific needs of the institutions, but also to become a broader child health portal.
“The website in 2001 was an amateurish affair and a disgrace to an internationally renowned centre for paediatric treatment, training and research. Run largely from the Research Office it was focused on one particular audience, uninspiring in design, reactive in updating and made little use of the potential of the internet. We needed someone to take it forward …
“David [South] was lead staff member for the website, recruiting and managing staff and suppliers, liaising with stakeholders inside and outside the organisations, planning work and seeking opportunities and partnerships. It is fair to say that the site made enormous strides under his leadership, winning a number of national and international awards, and leapfrogging to become one of the best NHS-linked sites in the UK.
“A number of areas were drastically improved, including design and navigation, patient information for families, press material, and the award-winning children’s site, which is now an international project with many different partners. David [South] project managed many projects in this time including linked sites for London IDEAS Genetics Knowledge Park, and the hospital charity site …” Stephen Cox, Chief Press Officer, Great Ormond Street Hospital for Children NHS Trust and the Institute of Child Health
took public consultation and consultant’s report and crafted and developed a strategy to implement the GOSH Child Health Web Portal
assembled team across two institutions
set clear milestones and brought project management methodology previously deployed with the United Nations
led on teaching new ways of project management for results
took GOSH brand forward for the digital age
advised colleagues on digital publishing and design
awarded additional funding
role model for NHS and government/charity sector. Awarded five stars in government review
launched major milestones with well-known figures, including Her Majesty the Queen, Madonna, and pop stars
significant media coverage of project
attracted funding not only for the GOSH Child Health Portal but also for other projects at the institutions
grew web traffic month-on-month, becoming one of the top online child health resources
website cited in many other resources. One of the goals of the project was to increase access to high-quality child health resources and to have them cited in books etc.
The Great Ormond Street Hospital Manual of Children’s Nursing Practices by Susan Macqueen, Elizabeth Bruce and Faith Gibson, John Wiley & Sons, 2012
Help! My Child’s in Hospital by Becky Wauchope, Marbec Family Trust, 2012
Oxford Desk Reference: Nephrology by Jonathan Barratt, Peter Topham and Kevin P.G. Harris, Oxford University Press, 2008
“There is increasing interest in young people’s participation in the design and delivery of health services. But young people’s views are not consistently sought or acknowledged, and they are still often marginalised in healthcare encounters. Drawing on original research and a diverse range of practice examples, Brady explores the potential for inclusive and diverse approaches to young people’s participation in health services from the perspectives of young people, health professionals and other practitioners. She presents a practical new framework, embedded in children’s rights, that shows how young people’s participation can be integrated into services in ways that are meaningful, effective and sustainable.”
The Human Genome Project (HGP) was officially declared complete in 2003. A rough draft of the human genome sequencing carried out by the HGP was formally announced in 2000 and the completed sequence was announced in 2003. This breakthrough spawned many initiatives, including Iceland’s deCode (below), and was reflected in the work I was called upon to undertake for the GOSH Child Health Portal at the time, such as designing websites for the London IDEAS Genetics Knowledge Park and the UK Newborn Screening Programme Centre (at bottom). I photographed the author of Our Genes, Steindor Erlingsson, in Reykjavik, Iceland for The Associated Press in 2002.
Cutting-edge medical research in China is promising to boost human health and development. Futuristic science is being conducted on a large scale and it is hoped this will increase the pace of discovery.
Around the world, rapid progress is being made in understanding the role played by genes and how they affect our overall health and susceptibility to diseases. Other developments are leading to the possibility of creating replacements for organs and other body parts that have been damaged through accidents, disease or genetic faults – without the need for organ donors.
Medical advances straight out of science fiction could be closer than many believe. By using machines and gene therapy, radical new methods will emerge to deal with damage done to human bodies as a result of accidents or disease. These solutions will become, in time, quicker, smaller and cheaper and will be available to more and more countries. They will spread outwards around the global South just as mobile phones and computing electronics have done.
In China, the government is investing heavily in this cutting-edge research and attracting investment and projects from around the world to increase the pace of progress in these areas.
In September 2013, Reuters reported that a 22-year-old man named Xiaolian in Fuzhou, China had a new nose grown on his forehead to replace his original nose that had been damaged in a car accident. Conventional reconstructive surgery was not possible, so this radical new approach was taken.
The advantages of growing a nose on the patient include a reduced chance of rejection by the body when the new organ is attached. Transplants of body parts from other people come with a high risk of rejection and require many drugs to prevent it. Using skin near where the transplant is to take place, on the face, improves the chances of success and the blood vessels in the forehead offer nourishment to grow the new nose.
The procedure works like this: tissue expanders are placed on the patient’s forehead. As it grows, the doctors cut the mass of tissue into the shape of a nose and cartilage from the patient’s ribs is placed inside to give the nose shape. The new proboscis (http://en.wikipedia.org/wiki/Proboscis) grows under the skin until it is the right size and then transplanted onto the patient’s face where their old nose was.
Many believe this is just the beginning and that in the future replacement organs will be also grown in a lab. And this is where the new medical technology of 3D bioprinting comes into play.
3D printing machines (http://www.k8200.eu/), or fabricators, can create 3D objects based on a design sent from a computer. This concept is now also being applied to biological materials with 3D bioprinters.
Hangzhou Dianzi University of Electronic Science and Technology (hdu.edu.cn) in China launched the Regenovo 3D Bio-printer in August 2013. It prints living tissue and looks like a silver metal frame with various nozzles situated above a platform for printing the tissue. Its makers claim it can print a liver in 40 minutes to an hour or an ear in 50 minutes.
A sheet of hydrogel is placed on the platform and then the bioprinter deposits cells into the hydrogel. As the process is repeated over and over again, layer after layer, a 3D biological structure emerges.
Unique Technology (sinounic.com) in Qingdao, Shandong province has also launched a 3D printer called “Re-human”. It is capable of printing at 15 microns and can operate in temperatures of between 0 and 300 degrees Celsius. Scientists there are working on clinical trials of 3D-printed tissue scaffolds and bones.
China is very advanced in the development of 3D manufacturing technology, and is home to the world’s largest 3D printers, developed by Dalian University of Technology (http://www.dlut.edu.cn/en/). Another Chinese company pioneering this technology is Shaanxi Hengtong Intelligent Machines (http://www.china-rpm.com/english/), which sells various laser-using rapid prototyping machines and 3D machines.
Around the world, bioprinting is currently being pioneered for printing heart valves, ears, artificial bones, joints, vascular tubes, and skin for grafts.
The number of scientific papers mentioning bioprinting tripled between 2008 and 2011 according to Popular Science. But why is this happening? Three things are occurring at once: sophisticated 3D printers are now available, there are significant advances in regenerative medicine, and CAD (computer-aided design) (http://en.wikipedia.org/wiki/Computer-aided_design) software continues to become more advanced.
San Diego, California’s Organovo (organovo.com), a company that designs and creates functional human tissues using 3D bioprinting, has big ambitions for the technology.
“Getting to a whole organ-in-a-box that’s plug-and-play and ready to go, I believe that could happen in my lifetime,” its chief technology officer, Sharon Presnell, told Popular Science.
In the field of gene science, China is also investing significant resources to make rapid progress. China is working to make its genetic research industry into one of the country’s pillar industries.
Beijing Genomics Institute (BGI) (http://www.genomics.cn/en/index) is the world’s largest genome-mapping institute, with more than 1,000 biological analysis devices working with top-of-the-line genome-sequencing machines. What makes BGI different is scale: it can handle data in vast quantities and industrialize its research, according to China Daily.
But what will they do with this information? By doing embryo screening, it will be possible to pick the brightest zygote (http://en.wikipedia.org/wiki/Zygote) and ensure an entire generation’s intelligence is increased by five to 15 IQ (intelligence quotient) points. This could have a significant impact on the country’s economic performance, the researchers believe, and help in the country making more rapid economic and development gains. This line of research is also seen globally as being fraught with ethical dilemmas and is controversial.
But the Chinese researchers believe the country’s economic productivity, business success, international competitiveness and the amount of innovation in the economy could all increase with an IQ boost.
The eggs are fertilized in the lab with the father’s sperm and the embryos are tested until they find the smartest one.
Embryo analysis could take place on a large scale in a few years. But it is not just better brains that are possible with this technique: choices can be made about hair and eye colors, and physical attributes such as body shape.
This level of research is benefiting from vast investments in higher education in China.
And it isn’t just human beings receiving the vast investment in gene research.
To help agriculture and agribusiness, the National Center for Gene Research (NCGR) (ncgr.ac.cn) is mapping and sequencing the rice genome, and genomes of other organisms. Since 2007, it has been using the latest generation sequencing technology to map the rice genome to identify common genetic factors. It has 50 million base pairs of rice genomic DNA sequences in its public database. It is hoped this will lead to more robust rice varieties that can withstand disease and climate fluctuations and help meet the food needs of a growing global population.
1) Wake Forest Institute for Regenerative Medicine: Wake Forest Innovations was created in 2012 as a new operating division of Wake Forest Baptist Medical Center. As the Medical Center’s technology commercialization arm, Wake Forest Innovations supports scholarship, investing in the innovative potential of academic and clinical communities and helping translate ideas and discoveries into valuable commercial products and services. Website: http://www.wakehealth.edu/WFIRM/
2) DEKA Research & Development: DEKA Research and Development Corporation is an established company focused on the development of radical new healthcare technologies that span a diverse set of applications. Website: http://www.dekaresearch.com/index.shtml
3) Organovo: Organovo design and create functional human tissues using proprietary three-dimensional bioprinting technology. The goal is to build living human tissues that are proven to function like native tissues. Website: http://www.organovo.com/
6) Autodesk is working on CAD software for bioprinting. Website: autodesk.co.uk
7) BGI Cognitive Genetics Project: BGI Cognitive Genomics is an interdisciplinary research group at BGI, one of the largest genomics institutes in the world. The focus is human cognition, with emphasis on the use of tools made available by rapid advances in DNA sequencing technology. Website: https://www.cog-genomics.org/
8) Institute of Genetics and Developmental Biology Chinese Academy of Sciences: The mission of the institute is to address fundamental questions in genetics and developmental biology and to develop new technologies for the uses in health care and agriculture sciences as well as to meet the nation’s strategic needs in science and technology. Scientists in the institute use both plant and animal models to address fundamental questions in life sciences, such as genetic control of growth and development, gene expression, signal transduction, structural and functional genomics, biotech and molecular breeding, bioinformatics and systems biology. As China owns the biggest agricultural market in the world, researchers in the Institute have also made significant efforts on water saving agriculture and agronomic studies, focusing on the improvement of crop productivity and quality as well as bio-safety. Website: http://english.genetics.cas.cn/au/
Development Challenges, South-South Solutions was launched as an e-newsletter in 2006 by UNDP’s South-South Cooperation Unit (now the United Nations Office for South-South Cooperation) based in New York, USA. It led on profiling the rise of the global South as an economic powerhouse and was one of the first regular publications to champion the global South’s innovators, entrepreneurs, and pioneers. It tracked the key trends that are now so profoundly reshaping how development is seen and done. This includes the rapid take-up of mobile phones and information technology in the global South (as profiled in the first issue of magazine Southern Innovator), the move to becoming a majority urban world, a growing global innovator culture, and the plethora of solutions being developed in the global South to tackle its problems and improve living conditions and boost human development. The success of the e-newsletter led to the launch of the magazine Southern Innovator.